Anaëlle Foucault-Dumas, PhD : "Nano-particles for healing"

During the 2016 L'Oréal-Unesco For Women In Science fellowships in France, Anaëlle Foucault-Dumas has introduced us her research domain, the nano-medication.

How do we reduce side-effects while increasing the effectiveness of treatments? This is the challenge for nano-medication, small capsules that transport medication to the place where their action is required, avoiding their circulation in the whole body and also any side-effects. “But nano-medication does not resolve everything: it is difficult to put the active substance into the capsule and its release is still not as precise as was hoped”, explains Anaëlle Foucault-Dumas, currently carrying out post-doctorate research at the Institut Galien Paris Sud. To overcome these difficulties, Anaëlle decided to replace capsules with nano-particles of palladium. They are the same size... But instead of releasing a therapeutic molecule, the nano-particles attach a marker to certain proteins implicated in an illness, indicating that they should “be destroyed” in cellular language. This will be an effective way to “limit side effects”, says Anaëlle Foucault-Dumas. 

The researcher is currently testing this innovative approach on thyroglobulin, a protein which, in excess, is responsible for serious illnesses such as hyperthyroidism. However, these applications could also be used in cancerous cells. “If we are successful, this approach will be a disruptive innovation in the emerging field of nano-medicine”, concludes the researcher, who works each day to push the limits of our knowledge.

Let's discover her performance:

For Women in Science

Before downloading this file

We confirm that the use of the Contents provided on this website is strictly for editorial purposes only.

We understand and confirm that any use, reproduction or representation of the Content provided on the Site (in whole or in part) or of the elements which comprise it, for commercial purposes whatsoever, is not authorized and violations in this regard shall invite strict legal action as per applicable laws & regulations.

We understand and confirm that the right to use the Content is on non-exclusive, non-transferable basis.

We hereby confirm that all information/statements/certificate in this database are provided without any warranty, express or implied, as to their legal effect, completeness and effects of any transaction under process may not be completely reflected.

We hereby confirm that all information/statements/certificate should be used in accordance with applicable laws. Use of information/statements/certificate shall be at my/ our own risk and L’OREAL shall not be responsible for the same.

We do hereby confirm that by using this Site, I/we am/are deemed to have accepted these Terms of Use without reserve.

I agree to the terms of use