Ai Ing Lim, "Zooming in on immune system intelligence"

Fellow 2017 L'Oréal-Unesco For Women In Science, Ai Ing Lim is seeking to characterize better « Innate Lymphoid Cells ».

The immune system is made up of a collection of cells whose function is to defend the organism. They include the recently identified “innate lymphoid cells” (ILC), which play a major role in the initial phases of the immune response. 

Ai Ing LIM, from Muar in Malaysia, was able to pursue her studies in science thanks to the support of her family. Now a PhD student with the Innate Immunity Unit at the Institut Pasteur, Université Paris Diderot, the young researcher is working to achieve better characterization of ILC. Through her research, she identified and isolated from human blood, a particular type of cell which can develop into four different types of ILC, and which can therefore be considered an “ILC precursor” cell: "This work enabled me to come up with a new ILC genesis model in which the precursor cells circulating in the blood adapt their mode of action depending on the type of tissue they penetrate.” 

Using ILC precursors, it is now possible to manufacture different types of ILC that could be used in cell therapy to treat infectious diseases, allergies and some cancers.

Watch her performance on video and let us know @4womeninscience

For Women in Science

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